Lead Poisoning: Awareness in Medical and Non-Medical Population of Karachi

Authors

  • Sana Ahmed Sarfaraz Faculty of Pharmacy, Jinnah University for Women Karachi
  • Aqsa Naz Faculty of Pharmacy, Jinnah University for Women Karachi
  • Amber Shahid Faculty of Pharmacy, Jinnah University for Women Karachi
  • Maryam Qayyum Faculty of Pharmacy, Jinnah University for Women Karachi

DOI:

https://doi.org/10.21467/ajgr.1.1.3-13

Abstract

Lead is a heavy element, also termed as nerve poison. Lead interferes with a variety of body processes and is toxic to many organs and tissues, including the central nervous system. The purpose of this study is to evaluate awareness regarding lead poisoning, factors that cause lead poisoning, symptoms, effect on enzymes, treatment and preventive measure that can be adopted to reduce lead poisoning in our population. It is a descriptive cross sectional survey based study consisting of 300 individuals comprising of 100 medical professionals and 200 laypersons (100 from Literate and 100 from Illiterate Population). The study was carried out from different locations in Karachi and answers were recorded as open and close ended. Our study showed that 95% medical professionals, 53% Literate layperson whereas only 29% Illiterate layperson were aware about lead poisoning. 38% Literate, 27% Illiterate and 54% medical professional knew about the sources of lead poisoning. 82% medical professionals, 17% Literate laypersons were aware about pharmacological intervention and there was no awareness among Illiterate Population.

Keywords:

Lead poisoning, Nerve toxin, CNS damage, dietary sources, Chelation therapy

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Author Biographies

Sana Ahmed Sarfaraz, Faculty of Pharmacy, Jinnah University for Women Karachi

Faculty of Pharmacy Jinnah University for Women

Aqsa Naz, Faculty of Pharmacy, Jinnah University for Women Karachi

Undergraduate Student

Clinical Pharmacy

Course code 603

Amber Shahid, Faculty of Pharmacy, Jinnah University for Women Karachi

Undergraduate Student

Clinical Pharmacy

Course code 603

Maryam Qayyum, Faculty of Pharmacy, Jinnah University for Women Karachi

Undergraduate Student

Clinical Pharmacy

Course code 603

References

Mark C. Henry, Edward R. Stapleton, “Poisoning And Overdoses” , EMT Prehospital Care, Published by Jones & Bartlet, 2010; 4th edition:362

Carol D Tamparo, Marcia A Lewis, “Effect Of Physical and Chemical Agents” , Diseases of the Human Body,Published by F.A.Devis Company,2011;5th edition:13

Nicholas Bateman, Robert D. Jefferson, Dr., John P. Thompson, Dr., Simon H. L. Thomas, “Epidemiology of Poisoning” , Toxicology, Published by Oxford University Press 198 Medison Avenue ,2014 ; 1st edition:2

By Dorothy A. Drago , “Poisoning” , Living Safely, Aging Well: A Guide to Preventing Injuries at Home ,Published by Johns Hopkins University Press ,2013: 73

Stephen R.Thorn and Lon w.Keim , “Carbon monoxide poisoning: A Review epidemiology, pathophysiology, clinical findings, and treatment options including hyperbaric oxygen therapy” , Journal of Toxicology: Clinical Toxicology, published by Taylor & Francis Group, 2008; 27(3):141-156

L F Prescott, R N Illingworth, J A Critchley, M J Stewart, R D Adam, A T Proudfoot , “Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning” , Br Med Journal , 1979; 2:1097

Sven Hernberg, “Lead Poisoning in a Historical Perspective” , American Journal Of Industrial Medicine, published by Wiley-Liss,Inc.,2000; 38:244-254

Nikolas C Papanikolaou, Eleftheria G Hatzidaki, Stamatis Belivanis, George N Tzanakakis, Aristidis M Tsatsakis, “Lead toxicity update. A brief review.”, Journal of Medical Science,2005; 11:10

Mustafa Aral , “Air Pathway Analysis” , Environmental Modeling and Health Risk Analysis (Acts/Risk), Springer publication,2010:97

Naser A. Anjum, Iqbal Ahmad, M. Eduarda Pereira, Armando C. Duarte, Shahid Umar, Nafees A. Khan, “Current Status of Toxic Metals Addition to Environment And its Consequences”, The Plant Family Brassicaceae: Contribution Towards Phytoremediation, Springer publication, 2012; 21:59

Randolph K. Byers, Elizabeth E. Lord, “Late Effects Of Lead Poisoning On Mental Development” , JAMA Pediatrics , 1943; 66(5):471-494.

Edward L. Baker, Jr., David S. Folland, T. A. Taylor, Myron Frank, Wendy Peterson, George Lovejoy, Dennis Cox, Jere Housworth, and Philip J. Landrigan. “Lead Poisoning in Children of Lead Workers — Home Contamination with Industrial Dust” , The New England Journal Of Medicine , 1977; 296:260-261

Cathie Robertson , “ Lead Exposure In Children Affects Brain and Behaviour” ,Safety,Nutrition & Health In Early Education, 6th edition: 387

Jessic Wolpaw Reyes, “Lead Exposure And Behaviour : Effects On Antisocial And Risky Behaviour Among Children And Adolescents” ,2012:6-7

Patrick, Lyn. "Lead toxicity, a review of the literature. Part I: exposure, evaluation, and treatment." Alternative Medicine Review ,2006; 11(1): 5

O A Levander, “Lead toxicity and nutritional deficiencies” , PMC Journal, 1979 ; 29 : 115–125.

Hwan-Cheol Kim, Tae-Won Jang, Hong-Jae Chae, Won-Jun Choi, Mi-Na Ha, Byeong-Jin Ye, Byoung-Gwon Kim, Man-Joong Jeon, Se-Yeong Kim, and Young-Seoub Hong, “Evaluation and management of lead exposure” , PMC Journal, 2015; 27: 30.

Jennifer A. Lowry, “Management of the Child with Elevated Blood Lead Concentrations” , Oral Chelation Therapy for patients with lead poisoning ,2010:8

J N Gordon, A Taylor, and P N Bennett , “Lead poisoning: case studies”,PMC journal, 2002; 53(5): 451–458.

Goldberg A, Smith JA, Lochhead AC. “Treatment of Lead-poisoning with Oral Penicillamine” ,British Medical Journal,1963; 1(5340):1270-1275.

E Friedheim a, J.H Graziano b, D Popovac c, D Dragovic c, B Kaul d, “Treatment of Lead Poisoning by 2,3-Dimercaptosuccinic acid”, The Lancet, 1978; 2(8102):1234-1236

Shuangxing Hou, Lianfang Yuan, Pengpeng Jin, Bojun Ding,1 Na Qin, Li Li,Xuedong Liu,Zhongliang Wu,Gang Zhao,and Yanchun Deng, “A clinical study of the effects of lead poisoning on the intelligence and neurobehavioral abilities of children” , PMC journal , 2013; 10: 13.

Jia Cao ,Minming Li ,Yu Wang,Guangjun Yu ,Chonghuai Yan , “ Environmental Lead Exposure among Preschool Children in Shanghai, China: Blood Lead Levels and Risk Factors”,PMC journal , 2014; 9(12):e113297

I Romieu, E Palazuelos, M Hernandez Avila, C Rios, I Muñoz, C Jimenez, and G Cahero , “Sources of lead exposure” , PMC journal , 1994; 102(4): 384–389.

Jerome O. Nriagu, a, Mary L. Blanksonb, Kwamena Ocranc, “Childhood lead poisoning in Africa: a growing public health problem” ,Science Of The Total Environment, Published by Elsevier B.V,1996;181(2):93-100

J.S.Carra, “Lead poisoning exposure” ,Lead poisoning , 1995: 304

Robert Brochin, “Cellular Effect of Lead Poisoning And Its Clinical Picture”, GU Journal of Health Sciences ,2008; 5:2

Jacquelyn Cafasso , “Lead Poisoning” , Health Line ,2016: 1-8

Namrata Chhabra, “ Effect of Lead poisoning on heme biosynthesis pathway” Clinical cases- Biochemistry For Medics , 2015 :1

Michael R. Moore ,Abraham Goldberg ,Albert A. C. Yeung-Laiwah, “Lead Effects on the Heme Biosynthetic Pathway Relationship to Toxicity” , Annals of The New York Academy of Sciences, 1987:191

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Published

2016-12-27

Issue

Section

Graduate Survey Articles

How to Cite

[1]
S. A. Sarfaraz, A. Naz, A. Shahid, and M. Qayyum, “Lead Poisoning: Awareness in Medical and Non-Medical Population of Karachi”, Adv. J. Grad. Res., vol. 1, no. 1, pp. 3–13, Dec. 2016.